PRX-T33 Needle-Free Skin Revitalization
PRX-T33 is a non-invasive biorevitalization treatment designed to improve skin quality, firmness, and tone—without downtime
FDA-Approved Technology
PRX-T33 is an FDA-approved topical biostimulator designed to stimulate collagen production without damaging the skin surface. Unlike traditional chemical peels, PRX works at the dermal level, promoting skin regeneration while maintaining epidermal integrity.
- Skin texture and overall tone
- Enlarged pores
- Fine lines and deep wrinkles
- Hyperpigmentation and melasma
- Dullness and early signs of aging
PRX-T33 delivers visible rejuvenation with minimal downtime, making it suitable for the face, under-eye area, neck, and body. It is an excellent option for patients seeking skin tightening, brightening, and long-term collagen stimulation without peeling or extended recovery.
How PRX Works
PRX supports dermal regeneration by encouraging collagen and elastin activity while preserving the skin barrier. The treatment works below the surface to improve overall skin quality without triggering surface inflammation.
Key Benefits
- ✓Improves firmness and elasticity
- ✓Smooths skin texture
- ✓Brightens uneven tone
- ✓Reduces the appearance of fine lines
- ✓Supports hydration and skin resilience
Treatment Experience
Approximate treatment time: 20–30 minutes
Needle-free and non-invasive
No anesthesia required
Generally comfortable
No downtime or recovery period
Results & Treatment Plan
Some improvement may be noticed after the first session. Optimal results are typically achieved with a series of treatments. Results develop gradually and build over time.




Who It’s For
PRX is suitable for all skin types and tones and can be performed year-round. It is commonly chosen by patients seeking skin improvement without aggressive treatments or downtime.
Learn More About PRX
PRX1
V-Line Aesthetics
PRX2
V-Line Aesthetics
PRX3
V-Line Aesthetics
PRX Explainer Video
Expert Insights: Module One
Dr. Alli discusses the science behind PRX
Expert Insights: Module Two
Advanced applications and treatment protocols
PRX Treatment Options
PRX Derm Perfexion
Focus: Firmness, elasticity, hydration, and early signs of aging
PRX Plus
Focus: Uneven tone, texture, hyperpigmentation, and visible signs of aging









FAQs
PRX-T33 or Derm Perfexion (as known in USA) is a needle-free, topical skin revitalization treatment designed to stimulate collagen activity beneath the surface of the skin. Unlike traditional chemical peels, it works without causing visible peeling or damage to the outer layer of the skin.
PRX is not considered a traditional chemical peel. While it contains trichloroacetic acid (TCA), it is formulated to bypass surface exfoliation and instead stimulate the deeper layers of the skin. Because of this, it is sometimes referred to as a “no-peel” or “reverse peel” treatment.
PRX uses a combination of ingredients to activate the dermal and basal layers of the skin. The formula supports collagen stimulation, cellular renewal, and overall skin vitality while preserving the skin barrier and minimizing surface irritation.
PRX may help improve: firmness and elasticity, uneven texture, fine lines and early signs of aging, hyperpigmentation and uneven tone, acne scarring and surface irregularities, and overall skin quality and hydration.
Most patients describe a mild tingling or warming sensation during application. The treatment is generally well tolerated and does not require numbing or anesthesia.
A typical PRX treatment session lasts approximately 30–45 minutes, depending on the area being treated and the number of applications performed during the session.
PRX does not require downtime. Most patients return to normal activities immediately after treatment. Some mild redness, warmth, or tightness may occur temporarily.
Visible peeling is uncommon. Some patients may experience very light flaking, particularly in thicker skin areas, but this is significantly less than with traditional chemical peels.
PRX is suitable for most skin types and tones and can be performed year-round. It is often chosen by patients looking for skin improvement without aggressive treatments or recovery time.
PRX may not be appropriate for individuals who are pregnant or breastfeeding, allergic to any ingredients in the formula, experiencing active skin infections/open wounds/irritation in the treatment area, or have highly reactive skin. A consultation is required to determine suitability.
Treatment plans vary depending on skin goals and concerns. Many patients benefit from an initial series of treatments, followed by periodic maintenance sessions. Your provider will customize a plan based on your needs.
Results develop gradually and can be long-lasting with proper skincare and maintenance treatments. Ongoing sessions may be recommended to support continued skin quality improvement.
Yes. PRX is often combined with other aesthetic treatments as part of a comprehensive skin plan. Combination treatments are determined by your provider during consultation.
Ready to Revitalize Your Skin?
Schedule a consultation to determine which PRX treatment is appropriate for your skin goals.
Text/Call: 909.839.0714